The Journal of Analytical Toxicology

Technical Note: Papain Adulteration in 11-nor-Δ9-Tetrahydrocannabinol-9-carboxylic Acid-Positive Urine SamplesCase Report: Postmortem Increase of Flecainide Level in Cardiac Blood

Technical Note: Detection of 1-Benzylpiperazine and 1-(3-Trifluoromethylphenyl)-piperazine in Urine Analysis Specimens Using GC-MS and LC-ESI-MS

Technical Note: Detection of 1-Benzylpiperazine and 1-(3-Trifluoromethylphenyl)-piperazine in Urine Analysis Specimens Using GC-MS and LC-ESI-MS

Issue Date: July/August 2008
Volume Number: 32
Issue Number: 6
Page Numbers: 444–450
Authors: Shawn P. Vorce, Justin M. Holler, Barry Levine, and Marilyn R. Past
Price (Article): $40.00
Ask a question about this product
Shawn P. Vorce, Justin M. Holler, Barry Levine, and Marilyn R. Past
Division of Forensic Toxicology, The Armed Forces Medical Examiner System, Armed Forces Institute of Pathology, 1413 Research Boulevard, Building 102, Rockville, Maryland 20850-3125

Designer piperazines, such as 1-benzylpiperazine (BZP) and 1-(3-trifluoromethylphenyl)-piperazine (TFMPP), are widely available and have become popular party drugs throughout the world. Used in many countries as legal alternatives to methamphetamine and ecstasy, these designer piperazines exhibit several of the same stimulant and psychoactive properties of their illicit counterparts. Presented is a case study of seven urine analysis specimens analyzed for designer piperazines. A full scan gas chromatography-mass spectrometry screen detected the presence of BZP and TFMPP in all seven specimens. Confirmation using liquid chromatography-electrospray ionization-mass spectrometry operating in selected ion monitoring mode (SIM) yielded urinary concentrations ranging from 13.0 to 429.1 mg/L and 0.79 to 25.4 mg/L for BZP and TFMPP, respectively

Journal of Analytical Toxicology, July/August 2008, Volume 32, Number 6, pages 444–450.

Reproduction (photocopying) of editorial content without publisher's permission is prohibited.


:

Customer Reviews:

There are yet no reviews for this product.
Please log in to write a review.


Shopping Cart

Your Cart is currently empty.
The Journal of Analytical Toxicology Articles Technical Note: Detection of 1-Benzylpiperazine and 1-(3-Trifluoromethylphenyl)-piperazine in Urine Analysis Specimens Using GC-MS and LC-ESI-MS

View Sample Issue

sample

Current Issue

Correlations Between Phthalate Metabolites in Urine, Serum, and Seminal Plasma from Young Danish Men Determined by Isotope Dilution Liquid Chromatography Tandem Mass Spectrometry
Correlations Between Phthalate Metabolites in Urine, Serum, and Seminal Plasma from Young Danish Men Determined by Isotope Dilution Liquid Chromatography Tandem Mass Spectrometry

Urinary Concentrations of Gamma-Hydroxybutyric Acid and Related Compounds in Pregnancy
Urinary Concentrations of Gamma-Hydroxybutyric Acid and Related Compounds in Pregnancy

Uptake and Distribution of the Abused Inhalant 1,1-Difluoroethane in the Rat
Uptake and Distribution of the Abused Inhalant 1,1-Difluoroethane in the Rat

Stability of the Tobacco-Specific Nitrosamine 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol (NNAL) in Urine Samples Stored at Various Temperatures
Stability of the Tobacco-Specific Nitrosamine 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol (NNAL) in Urine Samples Stored at Various Temperatures

Identification and Quantification of Nicotine Biomarkers in Human Oral Fluid from Individuals Receiving Low-Dose Transdermal Nicotine: A Preliminary Study
Identification and Quantification of Nicotine Biomarkers in Human Oral Fluid from Individuals Receiving Low-Dose Transdermal Nicotine: A Preliminary Study

Short Communication: The Prevalence of Alcohol and Drugs in Sampled Oral Fluid is Related to Sample Volume
Short Communication: The Prevalence of Alcohol and Drugs in Sampled Oral Fluid is Related to Sample Volume

A Simple and Sensitive Method for the Determination of Propofol in Human Solid Tissues by Gas Chromatography–Mass Spectrometry
A Simple and Sensitive Method for the Determination of Propofol in Human Solid Tissues by Gas Chromatography–Mass Spectrometry

Technical Note: Comparison of Ethanol and Other Drugs-of-Abuse Concentrations in Whole Blood Stored in Venoject® Glass and Plastic and in Venosafe™ Plastic Evacuated Tubes
Technical Note: Comparison of Ethanol and Other Drugs-of-Abuse Concentrations in Whole Blood Stored in Venoject® Glass and Plastic and in Venosafe™ Plastic Evacuated Tubes

Screening and Quantitative Determination of Twelve Acidic and Neutral Pharmaceuticals in Whole Blood by Liquid–Liquid Extraction and Liquid Chromatography–Tandem Mass Spectrometry
Screening and Quantitative Determination of Twelve Acidic and Neutral Pharmaceuticals in Whole Blood by Liquid–Liquid Extraction and Liquid Chromatography–Tandem Mass Spectrometry

Quantification of Methadone and its Metabolite 2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine in Third Instar Larvae of Lucilia sericata (Diptera: Calliphoridae) Using Liquid Chromatography–Tandem Mass Spectrometry
Quantification of Methadone and its Metabolite 2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine in Third Instar Larvae of Lucilia sericata (Diptera: Calliphoridae) Using Liquid Chromatography–Tandem Mass Spectrometry

Books

Analytical Toxicology of Benzodiazepines
Analytical Toxicology of Benzodiazepines